Chapter 6: PD-L1 CAR T Cell Therapy: A Potential Treatment for Non-Small Cell Lung Cancer
Authors: Janice Li, Jasmine Mudhur, Adhiba Nilormi, Soha Shabooti, Natasha Weikmann
Learning Objectives
After reading this chapter, you will be able to:
- Define non-small cell lung cancer (NSCLC) and its subtypes.
- Describe the causes, risk factors, demographics, clinical symptoms, and the diagnostic process for NSCLC.
- Identify the advantages and disadvantages of current clinical treatments.
- Explain how CAR T cells are created, how they function, and how they can be used as a treatment for cancer.
- Understand some future endeavors in the field of lung cancer research, including precision oncology and the use of liquid biopsies.
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EXPERT’S CORNER:
Dr. Natasha Leighl is a medical oncologist and the lung site lead at the Princess Margaret Cancer Center in downtown Toronto. Click below to listen to the interview.
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(Alec Koff – Background Music; Leighl) (Expert’s corner icon designed on Canva)
References
Alec Koff – Background Music. Medical Music, Health Background Music No Copyright / Medicine & Equipment Music. 9 Apr. 2020. YouTube, https://www.youtube.com/watch?v=iioIENY7ezk.
Is It Lung Cancer? https://www.webmd.com/lung-cancer/ss/slideshow-lung-cancer-surprising-signs. Accessed 5 Dec. 2020.
Leighl, Natasha. Expert’s Corner: Lung Cancer. Interview by Janice Li, 5 Dec. 2020, https://play.library.utoronto.ca/play/4a3ae2fc17a78d551d4cd9404e52bc66.