78 8.8 Futures directions for Vitamin B6

New Technology

The studies that were discussed concluded that additional vitamin B6 intake does have a great potential in alleviating the ASD social deficits. However, the treatment of autism requires the concept of personalized medicine where the dosage and interventions will be tailored to the patients’ needs. As discussed earlier, a deficiency and overdosage of vitamin B6 lead to neuropathy, therefore if we want to use vitamin B6 as a therapeutical treatment, it’s critical to get the dosage right. To ensure the right amount of vitamin B6 is prescribed to each individual, biotechnological companies can design a software or a non-invasive screening method to help evaluate the amount that is considered to be overdose based on the weight, height, and age of the individual. Technological advancements and new screening methods will further strengthen the field of personalized medicine and increase the likelihood of individuals that could benefit from using vitamin B6 to treat ASD.

Potential for combination therapy

Vitamin B6 is a great potential treatment for ASD, but only if we get the dosage right. The accessibility of vitamin B6 supplements makes it easy for consumers to take more than the standard amount as our diet also contributes to the levels of vitamin B6. The use of combination therapy can be a potential solution to this problem. If further research of the gut microbiota can identify an additional bacterial species that also share a similar function in stimulating the release of dopamine, then that compound can work together with vitamin B6 to alleviate the ASD symptoms. With the use of combination therapy, overdosage of vitamin B6 will less likely be since insufficient effects can be compensated with the other compound. The use of combination therapy can incorporate the use of vitamin B6 under safe levels and contribute to the alleviation of social deficits. Despite the potential, more research is needed to identify the bacterial species and test the possible adverse effects.

License

Selected Topics in Health and Disease (Vol. 3) Copyright © 2020 by Class of HMB422 2020 and Dr. William Ju. All Rights Reserved.

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