40 Biochemistry, Microbiology and Immunology
Biochemistry (BCH)
CH450 and CH451: Biochemistry – Defining Life at the Molecular Level∗
P.M. Flatt (Western Oregon University)
2019
Licence: CC BY-NC-SA 4.0
This course is designed for upper-division undergraduate students that are interested in learning about how life works. It is highly recommended for students that are interested in pursuing a graduate or professional degree in the medical sciences. The course is designed in two installments: Biochemistry I and Biochemistry II. The focus of Biochemistry II is on carbohydrate and lipid metabolism, as well as the processes of cellular energy production and utilization. Within these process, we will engage in the detailed exploration of biological macromolecule structure and function with emphasis on the mechanisms of protein/ligand binding, metabolic pathways and regulatory enzyme mechanisms.
Format: Online
Includes: Lecture notes, lectures on Youtube, PowerPoint slides
Suggested for:
BCH 2333 Introduction to Biochemistry
BCH 3120 General Intermediary Metabolism [section on enzymes]
BCH 4101 Human Genome Structure and Function [basics of chromosomes and genetics]
Cell Biology, Genetics, and Biochemistry for Pre-Clinical Students∗
Renee J. LeClair (Virginia Tech)
2021
Licence: CC BY-NC-SA 4.0
Cell Biology, Genetics, and Biochemistry for Pre-Clinical Students is an undergraduate medical-level resource for foundational knowledge across the disciplines of genetics, cell biology and biochemistry. This USMLE-aligned text is designed for a first-year undergraduate medical course that is delivered typically before students start to explore systems physiology and pathophysiology. The text is meant to provide the essential information from these content areas in a concise format that would allow learner preparation to engage in an active classroom. Clinical correlates and additional application of content is intended to be provided in the classroom experience. The text assumes that the students will have completed medical school prerequisites (including the MCAT) in which they will have been introduced to the most fundamental concepts of biology and chemistry that are essential to understand the content presented here. This resource should be assistive to the learner later in medical school and for exam preparation given the material is presented in a succinct manner, with a focus on high-yield concepts.
Formats: Pressbooks webbook, PDF, EPUB, and LibreTexts
Reviews: Open Textbook Library
Suggested for:
BCH 3120 General Intermediary Metabolism
BCH 3170 Molecular Biology
BCH 4101 Human Genome Structure and Function [basics of genetics]
Bioinformatics (BNF)
Creating a Virtual Bioinformatics Lab Module OER to Augment Protein Structure Function Capstone Courses
Zareen Amtul (University of Windsor)
Licence: CC BY-NC-SA 4.0
A set of 5 bioinformatics interactive H5P lab videos. There are accompanying lesson plans, quizzes, assignment with rubrics, and discussion components with rubrics. The videos focus on showing how to find, identify, manipulate, compare, and understand the sequence and 3D structure of model urease enzyme and an unknown protein. The first two videos illustrate the use of BLAST and PSI-BLAST search against a collection of non‐redundant protein databases, an ExPASy, and on‐line Metabolic Maps search by using the direct links to the GenBank™ entries from the BLAST output at the PDB site. The third video explains multiple sequence alignments/conservation and phylogenetic analysis by aligning the FASTA‐formatted sequences from the ExPASy site. The fourth video describes the use of ChEMBL database to perform a “Target” search of unknown protein sequence, find target associated assays and ligand efficiency data, and explore potential inhibitors/modulators of target protein. The last video is about predicting a protein structure and sequence comparison of proteins based on multiple sequence alignment & existing experimental data using SWISS-MODEL, and UCSF Chimera.
Formats: MP4, H5P, SRT, and text files
Suggested for:
BNF 5107 Applied Bioinformatics
Immunology (IMM)
No suggested OER at this time.
Microbiology and Immunology (MIC)
No suggested OER at this time.