Appendix A: Genetic and Genomic Online Resources
Compilation of Genetic and Genomic Online Resources
- OMIM: OMIM: Online Mendelian Inheritance in Man – A comprehensive database of human genes and genetic phenotypes, focusing on the relationship between genotype and phenotype.
- The Human Protein Atlas: The Human Protein Atlas– Provides detailed information on the tissue and cell distribution of proteins in the human body.
- GeneCards: GeneCards– An integrated database offering comprehensive information on all annotated and predicted human genes.
- ClinGen: ClinGen– Defines the clinical relevance of genes and variants for use in precision medicine and research.
- ClinVar: ClinVar– Archives and aggregates information about relationships among genomic variation and human health.
- GeneReviews: GeneReviews– Provides expert-authored, peer-reviewed disease descriptions focusing on diagnosis, management, and genetic counseling.
- NIH Gene: NIH Gene– A searchable database of genes, focusing on genomes that have been completely sequenced.
- Human Disease Genes: Human Disease Genes– Offers professional information about genes and their clinical consequences.
- ExpressAnalyst: ExpressAnalyst – A web-based platform for gene expression data analysis.
- Reactome: Reactome– A free, curated database of biological pathways.
- Comparative Toxicogenomics Database: Comparative Toxicogenomics Database – Provides information on the effects of environmental chemicals on human health.
- National Comprehensive Cancer Network: NCCN – Provides guidelines and resources for cancer care.
- National Library of Medicine (Gene): NLM Gene – Offers access to a wide range of biomedical and genomic information.
- The Expression Atlas: The Expression Atlas – Provides information on gene expression patterns under different biological conditions.
- Ensembl: Ensembl – A genome browser for vertebrate genomes.
- Gene Omnibus: Gene Omnibus– A repository for gene expression data.
- NCBI Genome Data Viewer: NCBI Genome Data Viewer– A genome browser for visualizing genomic data.
- UCSC Genome Browser: UCSC Genome Browser – A tool for exploring the human genome.
- SFARI Gene: SFARI Gene – A database for autism research.
- PhenX Toolkit: PhenX Toolkit – A repository of standardized measurement protocols.
- Gabriella Miller Kids First Data Resource Center: Kids First Data Resource Center – Provides biospecimens and genetic data related to pediatric cancer and structural birth defects.
- Health and Retirement Study: Health and Retirement Study – A longitudinal study of health and economic conditions in older adults.
- MetaboAnalyst: MetaboAnalyst – A tool for metabolomics data analysis.
- Plink: Plink – A toolset for whole-genome association analysis.
- Plink 1.9 Update: Plink 1.9 Update – An updated version of the Plink toolset.
- IGV Integrative Genomics Viewer: IGV – A tool for interactive exploration of large genomic datasets.
- GeneMania: GeneMania – A tool for predicting gene function and gene-gene interactions.
- Cytoscape: Cytoscape – A software platform for visualizing complex networks.
- OpenEpi.com: OpenEpi.com – Provides statistical calculators for epidemiology.
- Coriell Institute: Coriell Institute – A biobank for human cells and DNA.
- NHANES: NHANES – A program of studies designed to assess the health and nutritional status of adults and children in the United States.
- Pharmacogenomics:
- Cancer/Control Data Sets:
- GTEx – Provides data on gene expression and regulation in multiple human tissues.
- cBioPortal – A resource for exploring cancer genomics data.
- miRNA:
- miRDB – A database for miRNA target prediction.
- miRBase – A database of published miRNA sequences and annotations.
- miRNet – A tool for miRNA network analysis.
- TargetScan – A tool for predicting biological targets of miRNAs.
