3.5 – Reactions of Carboxylic Acids and Derivatives
Learning Objectives
- Predict products and write reaction schemes for the following reactions (no curved arrow mechanisms or energy profile diagrams required):
- Preparation and hydrolysis of an ester from a carboxylic acid and an alcohol, and the implications of the equilibrium reaction in terms of Le Châtelier’s Principle
- Predict products, write reaction schemes, draw curved arrow mechanisms, and draw energy profile diagrams, including all intermediates and transition states for the following reactions:
- Reaction of carbon dioxide with a Grignard reagent
- Preparation of an ester via a nucleophilic substitution reaction