40 Chapter Overview

Learning Objectives

After reading this chapter, you will be able to

  • Explain what happens during myocardial infarction
  • Identify the processes that occur post-myocardial infarction
  • Describe the relationship between the extracellular matrix and myocardial infarction
  • Describe the current treatments and their limitations
  • Appreciate the emerging use of injectable rHC for myocardial infarction treatment
  • Understand the efficacy and limitations of rHC in MI treatment

4.2 Introduction

Myocardial Infarction

The Extracellular Matrix and The Heart

Current Literature

4.3 Current Treatments

Introduction

Pharmacological

Surgeries

Growth factors

Cell-based therapies

Biomaterials

4.4 The Use of rHC in MI

Experimental design

Post-MI Cardiac Function and Morphology

Post-MI Vascularity and cardiomyocyte preservation

Mononuclear cell recruitment

In vitro assessment of rHC matrices

4.5 Efficacy of rHC in MI

Importance of findings

Current Literature

Limitations

4.6 Future Directions

4.7 Chapter Review

4.8 References

License

Selected Topics in Health and Disease (2019 Edition) Copyright © by Dr. Ju. All Rights Reserved.

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