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1.1 The Nature of Science

Escherichia coli bacteria as seen through an electron microscope and digital colorization.
Figure 1.1.1 Biologists may choose to study Escherichia coli (E. coli), a bacterium that is a typical resident of our digestive tracts but which is also sometimes responsible for disease outbreaks. This micrograph visualizes the bacterium using a scanning electron microscope and digital colorization. Image by Eric Erbe, digital colorization by Christopher Pooley, both of USDA, ARS, EMU, Public Domain

Scrolling through your social media feed or browsing the latest headlines, you’ll quickly notice how many aspects of biology are discussed daily. You might see reports of E. coli outbreaks in spinach or Salmonella contamination in chicken. Or you might read about the latest efforts to find cures for diseases like COVID-19, Alzheimer’s, and cancer. On a global scale, researchers are dedicated to protecting the planet, addressing environmental issues, and mitigating the effects of climate change. You might also see discussions about genetic engineering and CRISPR technology, revolutionizing medicine and agriculture by allowing scientists to edit genes precisely. All of these diverse efforts are related to biology.

Biology is the scientific study of life. That’s a simple definition to remember, but what does it mean? To fully understand biology, we must break the definition into several components. First, if biology is the scientific study of life, then what is science?

The Nature of Science

Science (from the Latin scientia, meaning “knowledge”) is a particular way of learning or knowing about the natural world.

The history of the past 500 years demonstrates that science is a compelling way of knowing about the world; it is mainly responsible for the technological revolutions that have occurred during this time. There are, however, areas of knowledge and human experience that science methods cannot apply. These include answering purely moral questions, aesthetic questions, or what can be generally categorized as spiritual questions. Science cannot investigate these areas because they are outside the realm of material phenomena, the phenomena of matter and energy, and cannot be observed and measured.

The scientific method is research with defined steps, including experiments and careful observation. The steps of the scientific method will be examined in detail later, but one of the most critical aspects of this method is the testing of hypotheses. A hypothesis is a suggested explanation for an event that can be tested. Hypotheses, or tentative explanations, are generally produced within the context of a scientific theory. A scientific theory is a generally accepted, thoroughly tested, and confirmed explanation for observations or phenomena. Scientific theory is the foundation of scientific knowledge. In addition, in many scientific disciplines (less so in biology), there are scientific laws, often expressed in mathematical formulas, describing how elements of nature will behave under certain conditions. There is no evolution of hypotheses through theories to laws as if they represented some increase in certainty about the world. Hypotheses are the day-to-day material that scientists work with, developed within the context of theories. Laws are concise descriptions of parts of the world that are amenable to formulaic or mathematical description.

Take a moment to test your knowledge of research terms by completing the drag-and-drop activity below.

Exercise 1.1.1

Text Description
Match each word with its definition.
  1. _____ A method of research with defined steps that include experiments and careful observation
  2. _____ A suggested explanation for an event
  3. _____ A generally accepted, thoroughly tested, and confirmed explanation for a set of observations or phenomena
  4. _____ Describe how elements of nature will behave under certain specific conditions
Possible answers:
  • Scientific Method
  • Hypothesis
  • Scientific Law
  • Scientific Theory

Answers:

  1. Scientific Method: A method of research with defined steps that include experiments and careful observation
  2. Hypothesis: A suggested explanation for an event
  3. Scientific Theory: A generally accepted, thoroughly tested, and confirmed explanation for a set of observations or phenomena
  4. Scientific Law: Describe how elements of nature will behave under certain specific conditions

Scientific Inquiry

One thing is common to all forms of science: the ultimate goal is “to know.” Curiosity and inquiry are the driving forces behind the development of science. Scientists seek to understand the world and its operations. Two methods of logical thinking are used: inductive reasoning and deductive reasoning.

 

Inductive Reasoning
Deductive Reasoning

In reality,  most scientific endeavours use a combination of descriptive science and hypothesis-based science. The boundary between these two main pathways of scientific study is often blurred. Observations lead to questions, questions lead to forming a hypothesis as a possible answer to those questions, and then the hypothesis is tested. Thus, descriptive science and hypothesis-based science are in continuous dialogue.

Basic and Applied Science

The scientific community has debated the value of different types of science for the last few decades. Is it valuable to pursue science to gain knowledge, or does scientific knowledge only have worth if we can apply it to solving a specific problem or bettering our lives? This question focuses on the differences between two types of science: basic science and applied science.

 

Basic Science
Applied Science
Logo for the Human Genome Project.
Figure 1.1.4 The Human Genome Project (1990-2003) generated the first sequence of the human genome. Image by .S. Department of Energy, Human Genome Project, Public Domain

Some may perceive applied science as “useful” and basic science as “useless.” A question these people might pose to a scientist advocating knowledge acquisition would be, “What for?” However, a careful look at the history of science reveals that basic knowledge has resulted in many remarkable applications of great value. Many scientists think that a basic understanding of science is necessary before an application is developed; therefore, applied science relies on the results generated through basic science. Other scientists think it is time to move on from basic science and instead find solutions to actual problems. Both approaches are valid. Some issues demand immediate attention; however, few solutions would be found without the help of the knowledge generated through basic science. Without basic science, it is unlikely that applied science would exist.

The Human Genome Project is another example of the link between basic and applied research. Initially, scientists analyzed and mapped human chromosomes to determine the DNA sequence and gene locations. The project eventually aimed to use this data for applied research, such as finding cures for genetic diseases.

While research efforts in both basic science and applied science are usually carefully planned, it is essential to note that some discoveries are made by serendipity, that is, utilizing a fortunate accident or a lucky surprise. Penicillin was discovered when biologist Alexander Fleming accidentally left a petri dish of Staphylococcus bacteria open. An unwanted mould grew, killing the bacteria. The mould turned out to be Penicillium, and a new antibiotic was discovered. Even in the highly organized world of science, luck can lead to unexpected breakthroughs when combined with an observant, curious mind.


Introduction to Biology” from Biology for Majors I by Shelli Carter and Lumen Learning is licensed under Attribution 4.0 International License, except where otherwise noted.

1.2 The Process of Science” from Biology and the Citizen by Colleen Jones is licensed under a Creative Commons Attribution 4.0 International License, except where otherwise noted.

The Nature of Science” from Principles of Biology by Catherine Creech is licensed under a Creative Commons Attribution 4.0 International License, except where otherwise noted.

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Biology Essentials 1 Copyright © 2025 by Kari Moreland is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, except where otherwise noted.