Lab 2: Confirmatory Testing by Mass Spectrometry in Forensic Context

The confirmatory testing in forensic science is most often done by using mass spectrometry based methods. The mass spectrometry allows for determination of structure and identity of the drug and its metabolites. In this lab, the mass spectrometry is used to detect the presence of a common medication, aspirin and its metabolite, salicylate.

Video

This video (9:14) documents in detail the full process of the electrospray ionization mass spectrometry (ESI-MS) instrument set-up, instrument calibration, calibration solution testing, and data analysis.

 

 

Data Sets and Worksheet

Clicking the data set links below will open the data sets for this lab in a new window. You will then have the option to download the pdf file if you choose to.

Data sets (experimental data) shared include the full mass spectra and partial mass spectra of chlorpromazine and sodium salicylate.

Clicking the worksheet link below will open the worksheet for this lab in a new window. You will then have the option to download the pdf file if you choose to.

License

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Forensic Toxicology by Dr. Sanela Martic is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, except where otherwise noted.

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